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Do not dispose of medications in wastewatere.gdown the sink or in the toiletor in household garbageAsk your pharmacist how to dispose of medications that are no longer needed or have expired.

Check with your doctor as soon as possible if any of the following side effects occur:

The most frequent adverse reaction to Zyloprim is skin rashSkin reactions can be severe and sometimes fatalThereforetreatment with Zyloprim should be discontinued immediately if a rash developssee WARNINGSSome patients with the most severe reaction also had feverchillsarthralgiascholestatic jaundiceeosinophilia and mild leukocytosis or leukopeniaAmong 55 patients with gout treated with Zyloprim for 3 to 34 monthsaverage greater than 1 yearand followed prospectivelyRundles observed that 3of patients developed a type of drug reaction which was predominantly a pruritic maculopapular skin eruptionsometimes scaly or exfoliativeHoweverwith current usageskin reactions have been observed less frequently than 1The explanation for this decrease is not obviousThe incidence of skin rash may be increased in the presence of renal insufficiencyThe frequency of skin rash among patients receiving ampicillin or amoxicillin concurrently with Zyloprim has been reported to be increasedsee PRECAUTIONS

Skin rashIf you develop a skin rashstop taking this medication and contact your doctorThe skin rash may be the first sign of a serious allergic reaction to the medication.

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