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The cardiotoxicity observed with XELODA includes myocardial infarction/ischemiaanginadysrhythmiascardiac arrestcardiac failuresudden deathelectrocardiographic changesand cardiomyopathyThese adverse reactions may be more common in patients with a prior history of coronary artery disease.

The efficacy endpoints for the two phase 3 trials are shown in Table 14 and Table 15.

Diarrhea nausea vomiting mouth and throat sores loss of appetite or decreased appetite excessive water loss from the bodydehydrationhand-foot syndrome irregular periods this can include temporary cessationusually resume after medication is completedor permanent cessation of menstrual periods depending on your age and other factors.

How it worksAntimetabolites kill cancer cells by acting as false building blocks in a cancer cell’s genescausing the cancer cell to die as it gets ready to divide.

Inactive ingredientsanhydrous lactosecroscarmellose sodiumhydroxypropyl methylcellulosemicrocrystalline cellulosemagnesium stearate and purified waterThe peach or light peach film coating contains hydroxypropyl methylcellulosetalctitanium dioxideand synthetic yellow and red iron oxides.

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