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For patients less than 3 years and for all other age groupsan immediate-release oral suspension dosage form is availableplease refer to the respective Summary of Product Characteristics

Do not restart therapy following severe skin rashskin rash combined with increased transaminases or other symptomsor hypersensitivity reaction.

The clinical relevance of these data in European populations has not been establishedFurthermorein the case Viramune is used as single dose to prevent vertical transmission of HIV-1 infectionthe risk of hepatotoxicity in mother and child cannot be excluded.

The additional studies showed that the prolonged-release tablets were as effective as the immediate-release tablets in HIV-infected patientsThey also showed that patients can be safely switched from immediateto prolonged-release tablets.

Limited human data are insufficient to determinerisk of infertility in humansbased on results from animal fertility studies conducted in ratstherapy may reduce fertility in females of reproductive potentialnot known if these effects on fertility are reversible.

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