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Administration of 20-30 g activated charcoal may be considered if possible within a few hours after overdose intake to decrease absorption of paroxetine.

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these medications are not well studied in patients with fibromyalgia but the available evidence indicates that immediate-release paroxetine may provide a small improvement in pain, sleep, and depression based on one trial comparing paroxetine to amitriptyline.

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therefore, drugs that alter gastric ph such as antacid drugs, proton pump inhibitors or histamine h2-receptor antagonists may affect plasma paroxetine concentrations in patients taking the oral suspension see section 4.


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