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When you first start taking metformin standard-release tablets you will be advised to increase the dose slowlyThis reduces the chances of getting side effects.

High insulin levels can cause thickening and darkening of the skinacanthosis nigricanson the back of the neckaxillaunder the armsand groin areaIn young women with PCOShigh insulin levels can cause the ovaries to make more androgen hormones such as testosteroneThis can cause increased body hairacneand irregular or few periodsHaving insulin resistance can increase your risk of developing diabetes.

Metformin reduces the amount of sugar your liver releases into your bloodIt also makes your body respond better to insulinInsulin is the hormone that controls the level of sugar in your blood.

That’s itrosiglitazoneWith Avandiathe reason I asked for this Avandiawhen I was in America in the early part of this yearthey had such a massive powerful write up about it that diabetics were on itThey have done so welltheir diabetes is in check and all the rest of itso I thoughtgo for itand I went for itmy whole entire body swellMy diabetes was up thereIt wasn’t doing nothing for meI was just like a pudding.

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